Relationship between vitamin B12 levels and insulin resistance in postmenopausal women from Colombia Caribbean / Relação entre níveis de vitamina B12 e resistência à insulina em mulheres na pós-menopausa da Colômbia Caribe

Introduction: The high prevalence of low vitamin B12 serum levels has been recognized as a public health problem in Latin America; however, the current magnitude of this deficiency in Colombia is uncertain. Low levels of vitamin B12 can induce clinical and subclinical hematological and neurological disorders. Epidemiological studies have demonstrated a relationship between vitamin B12 deficiency and cardiovascular diseases (CVDs). However, the role of vitamin B12 in insulin resistance has been poorly studied. Objective: This study aimed to evaluate the relationship between vitamin B12 serum levels and biochemical and anthropometric markers related to CVDs and insulin resistance in postmenopausal women from Colombia Caribbean. Methods: Correlational, descriptive study. By convenience sampling, 182 postmenopausal women from the medical consultation service of a health institution were linked. Serum vitamin B12 levels, anthropometric variables (body mass index, abdominal perimeter), and biochemical variables (glycemia, insulin, lipid profile, HOMA IR) were evaluated. Results: The average value of the vitamin B12 serum level was 312.5 ± 122.5 pg/mL (230.6 ± 90.4 pmol/L); 46.7% of the women had less than adequate levels of 300 pg/mL (> 221 pmol/L), and 9. 9% were deficient, with levels of less than 200 pg/mL (148 pmol/L). The women with metabolic syndrome were 63.7%, and according to HOMA IR, 52.7 % had insulin resistance. A significant inverse relationship was shown between serum vitamin B12 levels with basal glycemic (P =0.002) and HOMA-IR (P =0.040). Conclusions: A significant inverse relationship between vitamin B12 levels and basal glycemia and HOMA-IR was observed. These findings highlight vitamin B12 deficiency in postmenopausal women and suggest nutritional supplementation.Keywords: Vitamin B12, Insulin resistance, Diet, Postmenopause, Cardiovascular diseases (AU).

Introdução: A alta prevalência de baixos níveis séricos de vitamina B12 foi reconhecida como um problema de saúde pública na América Latina, mas a magnitude atual dessa deficiência na Colômbia é incerta. Baixos níveis de vitamina B12 podem induzir distúrbios hematológicos e neurológicos clínicos e subclínicos. Na verdade, estudos epidemiológicos demonstram uma relação entre deficiência de vitamina B12 e doenças cardiovasculares (DCVs). No entanto, o papel da vitamina B12 na resistência à insulina tem sido pouco estudado. Objetivo: O objetivo deste estudo foi avaliar a relação entre os níveis séricos de vitamina B12 e marcadores bioquímicos e antropométricos relacionados com doenças cardiovasculares e resistência à insulina em mulheres pós-menopáusicas da Colômbia Caribe. Métodos: Estudo correlacional, descritivo. Por amostragem de conveniência, foram vinculadas 182 mulheres na pós-menopausa do serviço de consulta médica de uma instituição de saúde. Níveis séricos de vitamina B12, variáveis antropométricas (índice de massa corporal, perímetro abdominal) e variáveis bioquímicas (glicemia, insulina, perfil lipídico, HOMA IR) foram avaliadas. Resultados: O valor médio do nível sérico de vitamina B12 foi de 312,5 ± 122,5 pg/mL (230,6 ± 90,4 pmol/L); 46,7% das mulheres tinham níveis abaixo do adequado de 300 pg/mL (> 221 pmol/L), e 9,9% eram deficientes, com níveis abaixo de 200 pg/mL (148 pmol/L).As mulheres com síndrome metabólica foram 63,7% e, segundo o HOMA IR, 52,7% apresentavam resistência à insulina. Uma relação inversa significativa entre os níveis séricos de vitamina B12 com glicemia basal (P = 0,002) e HOMA-IR (P = 0,040) foi mostrada. Conclusões: Foi observada uma relação inversa significativa entre os níveis de vitamina B12 e glicemia basal e HOMA-IR. Esses achados destacam a deficiência de vitamina B12 em mulheres na pós-menopausa e sugerem suplementação nutricional (AU).

Neuromuscular Alterations Associated with COVID-19. A Scientific Literature Review

Introduction: The COVID-19 pandemic has brought short, medium, and long-term consequences on the quality of life of those affected. Among the complications are those related to the involvement of the nervous system and the structures involved in body movement, with sequelae that may be transitory and/or definitive, and require rehabilitation. Objective: Identify the neuromuscular alterations that affect body movement, associated with COVID-19. Material and methods: A search was made for observational works published in the SCOPUS, PubMed, EBSCO, and Nature databases between January 2020 and June 2022 under the PRISMA methodology, to answer the PICO question: what are the neuromuscular alterations that can potentially affect movement, associated with COVID-19? The established filters were type of study, language, age, availability, publication dates. The MeSH terms were SARS-Cov-2, COVID-19, Long Covid, Motor Activity Neuromuscular Diseases, Neurological Disorders, Guillain-Barré Syndrome, Myelitis Transverse, Stroke, Patient, Peripheral Nervous System Diseases. The methodological quality was evaluated according to STROBE and the level of evidence was established according to CEBM. Results: In the first search, 645 articles were identified. 637 were discarded by filters, titles, duplicate abstracts, methodological quality, and level of evidence. There were 8 articles selected for the present review in which neuromuscular alterations of central and peripheral origin were identified, such as myalgias, fatigue, polyneuroradiculopathies, CNS inflammation, among others, with clinical manifestations that affect movement. Conclusion: COVID-19 is a multisystemic disease that can affect the nervous system with symptoms of neuromuscular alterations that compromise body movement.

Introducción: La pandemia por la COVID-19 ha traído consecuencias a corto, mediano y largo plazo sobre la calidad de vida de los afectados. Entre las complicaciones se encuentran aquellas relacionadas con la afectación del sistema nervioso y las estructuras involucradas en el movimiento corporal, con secuelas que pueden ser transitorias y/o definitivas, y requieren rehabilitación Objetivo: Identificar las alteraciones neuromusculares que afectan el movimiento corporal, asociadas a la COVID-19. Material y métodos: Se hizo una búsqueda de trabajos observacionales publicados en las bases de datos SCOPUS, PubMed, EBSCO y Nature entre enero de 2020 y junio de 2022 bajo metodología PRISMA, para dar respuesta a la pregunta PICO: ¿cuáles son las alteraciones neuromusculares que potencialmente pueden afectar el movimiento, asociadas a la COVID-19? Los filtros establecidos fueron tipo de estudio, idioma, edad, disponibilidad y fechas de publicación. Los términos MesH fueron SARS-Cov-2, COVID-19, Long Covid, Motor Activity Neuromuscular Diseases, Neurological Disorders, Guillain-Barré Syndrome, Myelitis Transverse, Stroke, Patient, Peripheral Nervous System Diseases. La calidad metodológica se evaluó según STROBE y el nivel de evidencia se estableció según CEBM. Resultados: En la primera búsqueda se identificaron 645 artículos. Posteriormente se descartaron 637 por filtros, títulos, resúmenes duplicados, calidad metodológica y nivel de evidencia. Así, quedaron seleccionados 8 para la presente revisión, en los cuales se identificaron alteraciones neuromusculares de origen central y periférico, como mialgias, fatiga, polineuroradiculopatías, inflamación del SNC, entre otras, con manifestaciones clínicas que afectan el movimiento. Conclusión: La COVID-19 es una enfermedad multisistémica que puede afectar el sistema nervioso con síntomas de alteraciones neuromusculares que comprometen el movimiento corporal.

Relación entre asimetrías en diferentes pruebas de salto y lesiones musculoesqueléticas en futbolistas profesionales de Colombia / Relation between asymmetries in different jump tests and musculoskeletal injuries in professional football players in Colombia

Objetivo:el objetivo del estudio fue identificar la relación entre los resultados de las pruebas saltabilidad horizontal y vertical con la incidencia las lesiones musculoesqueléticas de miembros inferiores en futbolistas de un club de la liga profesional colombiana. Materiales y métodos:se realizó un estudio analítico, exploratorio, en 30 futbolistas de la nómina profesional del Club Deportivo Atlético Junior F.C. Al inicio de la temporada se evaluaron las características antropométricas, así mismo como la saltabilidad y asimetrías funcionales de las extremidades inferiores a través de pruebas de saltos verticales (CMJ y CMJs) y horizontales (3-Hop Test). El análisis consistió en la comparación los registros de las variables estudiadas entre los futbolistas con (lesionados n=11) y sin lesión (no lesionados n=19) en el transcurso del primer semestre dela temporada 2019. Resultados:en los hallazgos no se encontraron diferencias estadísticas entre los grupos en las características biológicas, antropométricas y de composición corporal (p>0,05). Derivado de los hallazgos en la saltabilidad vertical, no se observaron diferencias significativas en las asimetrías funcionales entre grupos (p>0,05), sin embargo, si se encontraron diferencias en las pruebas de saltabilidad horizontal entre lesionados y no lesionados (p<0,01). Conclusión:de este estudio podemos concluir que, en comparación a los futbolistas profesionales sin lesiones, se encontraron significativamente mayores asimetrías funcionales detectadas a través de la prueba de saltabilidad horizontal en los deportistas con lesión.

Objetives:the goal of the study was to identify the relationship between horizontal and vertical jumping tests with the incidence of lower limb musculoskeletal injuries in soccer players of a professional league club in Colombia. Materials and methods:an analytical, prospective study was carried out on 30 players from the professional roster of Club Deportivo Atlético Junior F.C. At the beginning of the season the anthropometric characteristics and body composition were evaluated, as well as jumping and functional asymmetries of the lower extremities through vertical (CMJ and CMJs) and horizontal (3-Hop-Test) jumping tests. The analysis consisted in comparing the records of the variables studied between the players with (injured n=11) and without injury (not-injured n=19) during the first semester of the 2019 season. Results:no statistical differences were found between the groups in the biological, anthropometric and body composition characteristics (p> 0.05). Derived from the vertical jumping findings, no significant differences were observed in the asymmetries between groups (p> 0.05), however, significant asymmetries were found in the horizontal jumping tests between injured and uninjured players (p <0.01). Conclusion: from this studywe can conclude that unlike uninjured professional soccer players, there were significantly greater functional asymmetries identified through the horizontal jumping test in athletes with injuries

DETERMINANTES PARA LA PRÁCTICA DE ACTIVIDAD FÍSICA EN ESTUDIANTES UNIVERSITARIOS: UNA REVISIÓN DE LITERATURA / DETERMINANTS OF PHYSICAL ACTIVITY IN UNIVERSITY STUDENTS: A LITERARY REVIEW

La actividad física hace referencia al movimiento corporal que genera gasto energético, su práctica frecuente mejora las funciones físicas y mentales; el transporte activo, las actividades cotidianas y la recreación corresponden a la forma más común de actividad física. En Colombia la mayor parte de la población es inactiva; los niños son más activos pero esta condición disminuye con la edad, y el porcentaje de universitarios que realizan actividad física es bajo. Está práctica está condicionada por la motivación interna, la condición física, la disponibilidad de tiempo y el soporte social. El gusto por el deporte, el espíritu competitivo, el mejoramiento de la imagen corporal, el manejo del estrés y los beneficios para la salud son factores motivadores para la práctica de la actividad física en estudiantes universitarios; por otra parte la pereza, el miedo a lesionarse, la escases de escenarios deportivos y la inseguridad del entorno son las barreras más frecuentes para la realización de actividad física en esta población.

Physical activity refers to the body movement that generates energy expenditure, its frequent practice improves physical and mental functions; Active transportation, daily activities and recreation correspond to the most common form of physical activity. In Colombia the majority of the population is inactive, children are more active, but this condition decreases with age, the percentage of college students who engage in physical activity is low, this practice is conditioned by internal motivation, physical condition, Availability of time and social support. The taste for sports, the competitive spirit, the improvement of the corporal image, the management of the stress and the benefits for the health are motivating factors for the practice of the physical activity in university students; On the other hand, laziness, fear of injury, lack of sports scenarios and insecurity of the environment are the most frequent barriers to physical activity in this population.